China (Mainland)
Low price high purity 1226781-44-7 Omarigliptin(MK-3102) in stock CAS NO.1226781-44-7
- FOB Price: USD: 480.00-500.00 /Gram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,
- Available Specifications:
gram (1-5)Gramgram (5-10)Gram
- Product Details
Keywords
- 1226781-44-7
- Omarigliptin(MK-3102)
- low price Omarigliptin(MK-3102)
Quick Details
- ProName: Low price high purity 1226781-44-7 Oma...
- CasNo: 1226781-44-7
- Molecular Formula: C??H??F?N?O?S
- Appearance: powder
- Application: Omarigliptin(MK-3102) is a potent, sel...
- DeliveryTime: 3-5 days after received the 100% payme...
- PackAge: by bottle
- Port: Wuhan
- ProductionCapacity: 10 Gram/Week
- Purity: >=98%
- Storage: 4°C for 2 years and -20°C for 3 years
- Transportation: By courier ( Fedex, UPS, DHL, EMS, SF ...
- LimitNum: 1 Kilogram
- Solvent:: DMSO : 50 mg/mL (125.49 mM; Need ultra...
Superiority
Low price high purity 1226781-44-7 Omarigliptin(MK-3102) in stock
Omarigliptin(MK-3102) is a potent, selective and long-acting DPP-4 inhibitor with IC50 of 1.6 nM; highly selective over all proteases tested (IC50 > 67 μM). IC50 value: 1.6 nM [1] Target: DPP-4 inhibitor in vitro: Omarigliptin has weak ion channel activity (IC50 > 30 μM at IKr, Cav1.2, and Nav1.5). An expansive selectivity counterscreen (168 radioligand binding or enzymatic assays) was carried out at MDS Pharma. An IC50 > 10 μM was obtained in all assays. in vivo: When orally administered 1 h prior to dextrose challenge in an oral glucose tolerance test (OGTT), it significantly reduced blood glucose excursion in a dose-dependent manner from 0.01 mg/kg (7% reduction in glucose AUC) to 0.3 mg/kg (51% reduction).
| Molecular Weight |
398.43 |
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| Formula |
C??H??F?N?O?S |
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| CAS No. |
1226781-44-7 |
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| SMILES |
N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C=C4C3)C1 |
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| Shipping |
Room temperature in continental US; may vary elsewhere. |
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| Storage |
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We have more than 10g stock at hand with very low price and very good quality and if you need more we can make Customized specifically for you.
Details
Wuhan Jonk Biological technology Co.,Ltd is a leading supplier of phytochemical reference standards and small molecule compound for regulatory filing and quality testing or early stage R&D. We are professional in extraction, synthesis and purification. With more than 5,000 products for sale, we serve the universal leading research institutes, universities, contract research organizations and large pharmaceutical and biotech companies sincerely .