China (Mainland)
Low price high purity EGFR-IN-12 ( 879127-07-8) in stock CAS NO.879127-07-8
- FOB Price: USD: 480.00-500.00 /Gram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: T/T,
- Available Specifications:
gram (1-5)Gramgram (5-10)Gram
- Product Details
Keywords
- 879127-07-8
- EGFR-IN-12
- low price high purity EGFR-IN-12
Quick Details
- ProName: Low price high purity EGFR-IN-12 ( 8...
- CasNo: 879127-07-8
- Molecular Formula: C??H??F?N?O
- Appearance: powder
- Application: EGFR-IN-12 is a 4,6-disubstituted pyri...
- DeliveryTime: 3-5 days after received the 100% payme...
- PackAge: by bottle
- Port: Wuhan
- ProductionCapacity: 10 Gram/Week
- Purity: >=98%
- Storage: 4°C for 2 years and -20°C for 3 years
- Transportation: By courier ( Fedex, UPS, DHL, EMS, SF ...
- LimitNum: 1 Gram
- Solvent:: DMSO : 44 mg/mL (99.44 mM; Need ultras...
Superiority
Low price high purity EGFR-IN-12 ( 879127-07-8) in stock
EGFR-IN-12 is a 4,6-disubstituted pyrimidine and is a potent, ATP-competitive, irreversible and highly selective EGFR inhibitor with an IC50of 21 nM. EGFR-IN-12 also inhibits mutant EGFRL858R and EGFRL861Q with IC50s of 63 nM and 4 nM, respectively. EGFR-IN-12 displays strong selectivity for EGFR over HER4 (IC50 = 7640 nM) and a panel of 55 other kinases. EGFR-IN-12 induces cells apoptosis and has antitumor activity[1][2].
| Molecular Weight |
413.40 |
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| Formula |
C??H??F?N?O |
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| CAS No. |
879127-07-8 |
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| SMILES |
O=C(C1CC1)NC2=CC=CC(NC3=NC=NC(NC4=CC=CC(C(F)(F)F)=C4)=C3)=C2 |
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| Shipping |
Room temperature in continental US; may vary elsewhere. |
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| Storage |
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Details
Wuhan Jonk Biological technology Co.,Ltd is a leading supplier of phytochemical reference standards and small molecule compound for regulatory filing and quality testing or early stage R&D. We are professional in extraction, synthesis and purification. With more than 5,000 products for sale, we serve the universal leading research institutes, universities, contract research organizations and large pharmaceutical and biotech companies sincerely .